(-) -Maackiain
(-) -Maackiain is a pterocarpan phytoalexin produced from Sophora flavescens. (-) -Maackiain is toxic to several genera of fungal pathogens of legume and non legume hosts. (-) -Maackiain enhances the activation of NLRP3 inflammasome, inhibits the activation of NF-κB pathway, exhibiting thereby immunostimulatory and anti-inflammatory activities. (-) -Maackiain is orally active[1][2].
Product Specifications
CAS Number
[2035-15-6]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Fungal; NF-κB; NOD-like Receptor (NLR)
Type
Natural Products
Related Pathways
Anti-infection; Immunology/Inflammation; NF-κB
Applications
COVID-19-immunoregulation
Field of Research
Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/maackiain.html
Purity
99.91
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
OC1=CC=C([C@@]2([H])[C@@](C3=C(C=C4C(OCO4)=C3)O2)([H])CO5)C5=C1
Molecular Formula
C16H12O5
Molecular Weight
284.27
Precautions
H302, H315, H319, H335
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
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