MKK7(Phospho-Ser271/Thr275) Rabbit Polyclonal Antibody

The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically activates MAPK8/JNK1 and MAPK9/JNK2| and this kinase itself is phosphorylated and activated by MAP kinase kinase kinases including MAP3K1/MEKK1| MAP3K2/MEKK2|MAP3K3/MEKK5| and MAP4K2/GCK. This kinase is involved in the signal transduction mediating the cell responses to proinflammatory cytokines| and environmental stresses. Alternative splicing results in multiple transcript variants.

MKK7 ;Ser271/Thr275; Dual specificity mitogen-activated protein kinase kinase 7; MAP kinase kinase 7; MAPKK 7; EC 2.7.12.2; JNK-activating kinase 2; MAPK/ERK kinase 7; MEK 7; Stress-activated protein kinase kinase 4; SAPK kinase 4; SAPKK-4; SAPKK4; c-Jun N-terminal kinase kinase 2; JNK kinase 2; JNKK 2