LIN28A(Phospho-Ser200) Rabbit Polyclonal Antibody
Product Specifications
Background
This gene encodes a LIN-28 family RNA-binding protein that acts as a posttranscriptional regulator of genes involved in developmental timing and self-renewal in embryonic stem cells. The encoded protein functions through direct interaction with target mRNAs and by disrupting the maturation of certain miRNAs involved in embryonic development. This protein prevents the terminal processing of the LET7 family of microRNAs which are major regulators of cellular growth and differentiation. Aberrant expression of this gene is associated with cancer progression in multiple tissues.
CAS Number
9007-83-4
Synonyms
LIN28A ;Ser200 ; Protein lin-28 homolog A; Lin-28A; Zinc finger CCHC domain-containing protein 1
Host
Rabbit
Reactivity
Human, Rat, Mouse
Immunogen
Synthesized phosho peptide around human LIN28A (Ser200)
Clonality
Polyclonal
Applications
WB
Stability
-20°C for 1 year
Concentration
1 mg/ml
Antibody Type
Primary antibody
Isotype
IgG
Available Sizes
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