Adrenomedullin (Human, 1-25)

<strong>Adrenomedullin (Human, 1-25)</strong> <strong>Catalog number:</strong> MDP0693 <strong>CAS Number: </strong>330936-69-1 <strong>Sequence: </strong>Tyr-Arg-Gln-Ser-Met-Asn-Asn-Phe-Gln-Gly-Leu-Arg-Ser-Phe-Gly-Cys-Arg-Phe-Gly-Thr-Cys-Thr-Val-Gln-Lys (Disulfide bond between Cys16-Cys21) <strong>Amount:</strong> 500 ug <strong>Molecular Weight:</strong> 2927.2 g/mol <strong>Supplied as:</strong> Powder <strong>Applications:</strong> molecular tool for various biochemical applications <strong>Storage:</strong> -20 °C <strong>WARNING:</strong> For in vitro Research Use Only. NOT for use on humans or animals. <strong>Grade:</strong> Biotechnology grade. All products are highly pure. <strong>References:</strong> 1: Larrue C, Guiraud N, Mouchel PL, Dubois M, Farge T, Gotanègre M, Bosc C, Saland E, Nicolau-Travers ML, Sabatier M, Serhan N, Sahal A, Boet E, Mouche S, Heydt Q, Aroua N, Stuani L, Kaoma T, Angenendt L, Mikesch JH, Schliemann C, Vergez F, Tamburini J, Récher C, Sarry JE. Adrenomedullin-CALCRL axis controls relapse-initiating drug tolerant acute myeloid leukemia cells Nat Commun. 2021 Jan 18;12(1):422. 2: Chauhan M, Betancourt A, Balakrishnan M, Mishra A, Espinosa J, Shamshirsaz AA, Fox K, Belfort M, Yallampalli C. Calcitonin Gene Related Peptide, Adrenomedullin, and Adrenomedullin 2 Function in Uterine Artery During Human Pregnancy Endocrinology. 2022 Jan 1;163(1):bqab204. 3: Chen E, Chuang LS, Giri M, Villaverde N, Hsu NY, Sabic K, Joshowitz S, Gettler K, Nayar S, Chai Z, Alter IL, Chasteau CC, Korie UM, Dzedzik S, Thin TH, Jain A, Moscati A, Bongers G, Duerr RH, Silverberg MS, Brant SR, Rioux JD, Peter I, Schumm LP, Haritunians T, McGovern DP, Itan Y, Cho JH. Inflamed Ulcerative Colitis Regions Associated With MRGPRX2-Mediated Mast Cell Degranulation and Cell Activation Modules, Defining a New Therapeutic Target Gastroenterology. 2021 Apr;160(5):1709-1724. 4: Zhang F, Wu R, Zhou M, Blau SA, Wang P. Human adrenomedullin combined with human adrenomedullin binding protein-1 is protective in gut ischemia and reperfusion injury in the rat Regul Pept. 2009 Jan 8;152(1-3):82-7. 5: Ramos CG, Sun X, Johnson EB, Nelson HE, Gonzalez Bosc LV. Adrenomedullin expression in the developing human fetal lung J Investig Med. 2014 Jan;62(1):49-55. 6: Yang J, Wu R, Qiang X, Zhou M, Dong W, Ji Y, Marini CP, Ravikumar TS, Wang P. Human adrenomedullin and its binding protein attenuate organ injury and reduce mortality after hepatic ischemia-reperfusion Ann Surg. 2009 Feb;249(2):310-7. 7: Maybin JA, Battersby S, Hirani N, Nikitenko LL, Critchley HO, Jabbour HN. The expression and regulation of adrenomedullin in the human endometrium: a candidate for endometrial repair Endocrinology. 2011 Jul;152(7):2845-56. 8: Zhang S, Patel A, Moorthy B, Shivanna B. Adrenomedullin deficiency potentiates hyperoxic injury in fetal human pulmonary microvascular endothelial cells Biochem Biophys Res Commun. 2015 Sep 4;464(4):1048-1053. 9: Ye L, Zuo Y, Chen F, Xu Y, Zhang P, Yang H, Peng Q, Wang G, Shu X. Adrenomedullin Expression Is Associated With the Severity and Poor Prognosis of Interstitial Lung Disease in Dermatomyositis Patients Front Immunol. 2022 Jun 2;13:885142. <a href="https://pubmed.ncbi.nlm.nih.gov/19010904">10: Joshi BH, Leland P, Calvo A, Green JE, Puri RK. Human adrenomedullin up-regulates interleukin-13 receptor alpha2 chain in prostate cancer in vitro and in vivo: a novel approach to sensitize prostate cancer to anticancer therapy Cancer Res. 2008 Nov 15;68(22):9311-7. </a> <br><strong>Products Related to Adrenomedullin (Human, 1-25) can be found at</strong> <a href="https://moleculardepot.com/product-category/Peptides/"> Peptides</a>