Leucomycin A13
Leucomycin A13 is a macrolide antibiotic and a component of the leucomycin complex originally isolated from S. kitasatoensis. It is active against B. subtilis, S. aureus, M. luteus, and E. coli with MIC values of 0.16, 0.16, 0.08 and >10 μg/mL, respectively. It binds to ribosomes with an IC50 value of 1.2 μM in a radioligand binding assay.
Product Specifications
CAS Number
78897-52-6
Product Name Alternative
Kitasamycin A13
UNSPSC
12352005
Target
Antibiotic
Type
Natural Products
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/leucomycin-a13.html
Smiles
O=CC[C@@H](C[C@H]([C@H](/C=C/C=C/C[C@H]1C)O)C)[C@@H]([C@H]([C@@H](CC(O1)=O)O)OC)O[C@H](O[C@@H]2C)[C@@H]([C@H]([C@@H]2O[C@H](O[C@H]3C)C[C@@](O)([C@H]3OC(CCCCC)=O)C)N(C)C)O
Molecular Formula
C41H69NO14
Molecular Weight
799.98
References & Citations
[1]Tanaka, et al. Quantitative structure-activity relationships of O-acyl derivatives of leucomycin for antimicrobial and ribosome-binding activities. Chem. Pharm. Bull. (Tokyo) 33 (7), 2803-2808 (1985) .
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
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