EGF Receptor(Phospho-Tyr1148) Rabbit Polyclonal Antibody
Product Specifications
Background
The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.
CAS Number
9007-83-4
Synonyms
EGF Receptor ;Tyr1148; Epidermal growth factor receptor; EC 2.7.10.1; Proto-oncogene c-ErbB-1; Receptor tyrosine-protein kinase erbB-1
Host
Rabbit
Reactivity
Human, Rat, Mouse
Immunogen
Synthesized phosho peptide around human EGF Receptor (Tyr1148)
Clonality
Polyclonal
Applications
WB
Stability
-20°C for 1 year
Concentration
1 mg/ml
Antibody Type
Primary antibody
Isotype
IgG
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