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N-Acetylputrescine

Product Specifications

UNSPSC Description

N-Acetylputrescine (NAP) is an endogenous metabolite widely present in animals and plants. N-Acetylputrescine can be used as a biomarker for lung squamous cell carcinoma (SCCL) and Parkinson's disease (PD) for disease diagnosis[1][2][3].

Target Antigen

Endogenous Metabolite

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/n-acetylputrescine.html

Purity

99.54

Solubility

DMSO : 100 mg/mL (ultrasonic)|H2O : 100 mg/mL (ultrasonic)

Smiles

CC(NCCCCN)=O

Molecular Weight

130.19

References & Citations

[1]Liu R, et al. Plasma N-acetylputrescine, cadaverine and 1,3-diaminopropane: potential biomarkers of lung cancer used to evaluate the efficacy of anticancer drugs. Oncotarget. 2017 Jul 17;8(51):88575-88585. |[2]Pfanzagl B, et al. N-acetylputrescine as a characteristic constituent of cyanelle peptidoglycan in glaucocystophyte algae. J Bacteriol. 1996 Dec;178(23):6994-7. |[3]Peng K W, et al. Identification and Validation of N-Acetylputrescine in Combination With Non-Canonical Clinical Features As a Parkinson’s Disease Biomarker Panel[J]. bioRxiv, 2021: 2021.07. 23.453542.|[4]Menashe M, et al. Formulation of N-acetylputrescine and N1-acetylspermidine in cultured human lymphocytes. Biochem J. 1980 Apr 15;188(1):263-7.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light, stored under nitrogen)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-W342604/N-Acetylputrescine-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-W342604/N-Acetylputrescine-SDS-MedChemExpress.pdf

Clinical Information

Phase 3

CAS Number

5699-41-2

Available Sizes

Curated Selection

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