VEGFR2 Polyclonal Antibody

Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor| known as kinase insert domain receptor| is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation| survival| migration| tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors| including Rab GTPase| P2Y purine nucleotide receptor| integrin alphaVbeta3| T-cell protein tyrosine phosphatase| etc.. Mutations of this gene are implicated in infantile capillary hemangiomas.

VEGFR2; Vascular endothelial growth factor receptor 2; VEGFR-2; EC 2.7.10.1; Fetal liver kinase 1; FLK-1; Kinase insert domain receptor; KDR; Protein-tyrosine kinase receptor flk-1; CD antigen CD309