Rb(Phospho Ser780) Polyclonal Antibody
Product Specifications
Background
The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active| hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB)| bladder cancer| and osteogenic sarcoma.
CAS Number
9007-83-4
Synonyms
Retinoblastoma-associated protein; RB1; Retinoblastoma-associated protein; p105-Rb; pRb; Rb; pp110
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human Retinoblastoma around the phosphorylation site of Ser780. AA range:751-800
Clonality
Polyclonal
Applications
WB, IHC-p, IF, ICC, ELISA
Stability
-20°C for 1 year
Concentration
1 mg/ml
Molecular Weight
106159
Antibody Type
Primary antibody
Isotype
IgG
Available Sizes
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