PDGFR-alpha(Phospho Tyr849) Polyclonal Antibody
Product Specifications
Background
This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer| composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development| wound healing| and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome| somatic and familial gastrointestinal stromal tumors| and a variety of other cancers.
CAS Number
9007-83-4
Synonyms
Platelet-derived growth factor receptor alpha; PDGFRA; PDGFR2; RHEPDGFRA; Platelet-derived growth factor receptor alpha; PDGF-R-alpha; PDGFR-alpha; Alpha platelet-derived growth factor receptor; Alpha-type platelet-derived growth factor receptor; CD140 antigen-like family member A; CD14
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human PDGFRa around the phosphorylation site of Tyr849. AA range:816-865
Clonality
Polyclonal
Applications
WB, IHC-p, IF, ELISA
Stability
-20°C for 1 year
Concentration
1 mg/ml
Molecular Weight
122670
Antibody Type
Primary antibody
Isotype
IgG
Available Sizes
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