NFκB-p65(Phospho Ser536) Polyclonal Antibody
Product Specifications
Background
NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor| NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL| RELA| or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene| RELA. Four transcript variants encoding different isoforms have been found for this gene.
CAS Number
9007-83-4
Synonyms
Transcription factor p65; RELA; NFKB3; Transcription factor p65; Nuclear factor NF-kappa-B p65 subunit; Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3
Host
Rabbit
Reactivity
Human, Mouse, Rat, Monkey
Immunogen
The antiserum was produced against synthesized peptide derived from human NF-kappaB p65 around the phosphorylation site of Ser536. AA range:502-551
Clonality
Polyclonal
Applications
IF, ICC, WB, IHC-p, IP, ELISA
Stability
-20°C for 1 year
Concentration
1 mg/ml
Molecular Weight
60219
Antibody Type
Primary antibody
Isotype
IgG
Available Sizes
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