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NFκB-p65(Phospho Ser276) Polyclonal Antibody

Product Specifications

Background

NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor| NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL| RELA| or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene| RELA. Four transcript variants encoding different isoforms have been found for this gene.

CAS Number

9007-83-4

Synonyms

Transcription factor p65; RELA; NFKB3; Transcription factor p65; Nuclear factor NF-kappa-B p65 subunit; Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

The antiserum was produced against synthesized peptide derived from human NF-kappaB p65 around the phosphorylation site of Ser276. AA range:249-298

Clonality

Polyclonal

Applications

WB, IHC-p, IF, IP, ELISA

Stability

-20°C for 1 year

Concentration

1 mg/ml

Molecular Weight

60219

Antibody Type

Primary antibody

Isotype

IgG

Available Sizes

Frequently Asked Questions

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