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MEK-1(Phospho Thr386) Polyclonal Antibody

Product Specifications

Background

The protein encoded by this gene is a member of the dual specificity protein kinase family| which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases| also known as extracellular signal-regulated kinases (ERKs)| act as an integration point for multiple biochemical signals. This protein kinase lies upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon wide variety of extra- and intracellular signals. As an essential component of MAP kinase signal transduction pathway| this kinase is involved in many cellular processes such as proliferation| differentiation| transcription regulation and development.

CAS Number

9007-83-4

Synonyms

Dual specificity mitogen-activated protein kinase kinase 1; MAP2K1; MEK1; PRKMK1; Dual specificity mitogen-activated protein kinase kinase 1; MAP kinase kinase 1; MAPKK 1; MKK1; ERK activator kinase 1; MAPK/ERK kinase 1; MEK 1

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

The antiserum was produced against synthesized peptide derived from human MAP2K1 around the phosphorylation site of Thr386. AA range:344-393

Clonality

Polyclonal

Applications

WB, ELISA

Stability

-20°C for 1 year

Concentration

1 mg/ml

Molecular Weight

43439

Antibody Type

Primary antibody

Isotype

IgG

Available Sizes

Frequently Asked Questions

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