MEK-1(Phospho Thr386) Polyclonal Antibody
Product Specifications
Background
The protein encoded by this gene is a member of the dual specificity protein kinase family| which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases| also known as extracellular signal-regulated kinases (ERKs)| act as an integration point for multiple biochemical signals. This protein kinase lies upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon wide variety of extra- and intracellular signals. As an essential component of MAP kinase signal transduction pathway| this kinase is involved in many cellular processes such as proliferation| differentiation| transcription regulation and development.
CAS Number
9007-83-4
Synonyms
Dual specificity mitogen-activated protein kinase kinase 1; MAP2K1; MEK1; PRKMK1; Dual specificity mitogen-activated protein kinase kinase 1; MAP kinase kinase 1; MAPKK 1; MKK1; ERK activator kinase 1; MAPK/ERK kinase 1; MEK 1
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human MAP2K1 around the phosphorylation site of Thr386. AA range:344-393
Clonality
Polyclonal
Applications
WB, ELISA
Stability
-20°C for 1 year
Concentration
1 mg/ml
Molecular Weight
43439
Antibody Type
Primary antibody
Isotype
IgG
Available Sizes
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