RuBi-Glutamate (hexafluorophosphate sodium)

RuBi-Glutamate hexafluorophosphate sodium is a novel cage glutamate compound based on ruthenium photochemistry. RuBi-Glutamate hexafluorophosphate sodium can be excited at visible wavelengths and release glutamate after single or two-photon excitation. It has high quantum efficiency and can be used at low concentrations, partially avoiding the blocking of GABA energy transmission by other cage compounds. Two-photon release of RuBi-Glutamate hexafluorophosphate sodium has high spatial resolution and produces a physiodynamic excitatory response in a single dendritic spine[1].

Product Specifications

CAS Number

[2417096-44-5]

UNSPSC

12352005

Target

GABA Receptor

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/rubi-glutamate-hexafluorophosphate-sodium.html

Purity

82.94

Solubility

H2O : 19.41 mg/mL (ultrasonic; warming)

Smiles

[F-][P+5]([F-])([F-])([F-])([F-])[F-].O=C(O[Na])[C@H](CCC(O[Na])=O)[NH2][Ru+2]12([N]3=CC=CC=C3C4=CC=CC=[N]14)([N]5=CC=CC=C5C6=CC=CC=[N]26)[P](C)(C)C.[F-][P+5]([F-])([F-])([F-])([F-])[F-]

Molecular Formula

C28H32F12N5Na2O4P3Ru

Molecular Weight

970.54

References & Citations

[1]Fino E, et al. RuBi-Glutamate: Two-Photon and Visible-Light Photoactivation of Neurons and Dendritic spines. Front Neural Circuits. 2009 May 27;3:2.