IGF-IR(Phospho Tyr1165/Y1166) Polyclonal Antibody
Product Specifications
Background
This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
CAS Number
9007-83-4
Synonyms
Insulin-like growth factor 1 receptor; IGF1R; Insulin-like growth factor 1 receptor; Insulin-like growth factor I receptor; IGF-I receptor; CD antigen CD221
Host
Rabbit
Reactivity
Human, Mouse, Rat, Monkey
Immunogen
The antiserum was produced against synthesized peptide derived from human IGF1R around the phosphorylation site of Tyr1165/Tyr1166. AA range:1131-1180
Clonality
Polyclonal
Applications
WB, ELISA
Stability
-20°C for 1 year
Concentration
1 mg/ml
Molecular Weight
154793
Antibody Type
Primary antibody
Isotype
IgG
Available Sizes
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