C8AP2 Rabbit Polyclonal Antibody

This protein is highly similar to FLASH| a mouse apoptotic protein identified by its interaction with the death-effector domain (DED) of caspase 8. Studies of FLASH protein suggested that this protein may be a component of the death-inducing signaling complex that includes Fas receptor| Fas-binding adapter FADD| and caspase 8| and plays a regulatory role in Fas-mediated apoptosis. Alternative splicing results in multiple transcript variants encoding the same protein.