CRMP-2(Phospho Thr514) Polyclonal Antibody
Product Specifications
Background
This gene encodes a member of the collapsin response mediator protein family. Collapsin response mediator proteins form homo- and hetero-tetramers and facilitate neuron guidance| growth and polarity. The encoded protein promotes microtubule assembly and is required for Sema3A-mediated growth cone collapse| and also plays a role in synaptic signaling through interactions with calcium channels. This gene has been implicated in multiple neurological disorders| and hyperphosphorylation of the encoded protein may play a key role in the development of Alzheimer's disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
CAS Number
9007-83-4
Synonyms
Dihydropyrimidinase-related protein 2; DPYSL2; CRMP2; ULIP2; Dihydropyrimidinase-related protein 2; DRP-2; Collapsin response mediator protein 2; CRMP-2; N2A3; Unc-33-like phosphoprotein 2; ULIP-2
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human DRP-2 around the phosphorylation site of Thr514. AA range:480-529
Clonality
Polyclonal
Applications
WB, IHC-p, IF, ICC, ELISA
Stability
-20°C for 1 year
Concentration
1 mg/ml
Molecular Weight
62294
Antibody Type
Primary antibody
Isotype
IgG
Available Sizes
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