Cdc25A(Phospho Ser75) Polyclonal Antibody
Product Specifications
Background
CDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage| which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene| although its exact role in oncogenesis has not been demonstrated. Two transcript variants encoding different isoforms have been found for this gene.
CAS Number
9007-83-4
Synonyms
M-phase inducer phosphatase 1; CDC25A; M-phase inducer phosphatase 1; Dual specificity phosphatase Cdc25A
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized phospho-peptide around the phosphorylation site of human Cdc25A (phospho Ser75)
Clonality
Polyclonal
Applications
WB, IHC-p, IF, ELISA
Stability
-20°C for 1 year
Concentration
1 mg/ml
Molecular Weight
59087
Antibody Type
Primary antibody
Isotype
IgG
Available Sizes
Frequently Asked Questions
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