IF4A3 Rabbit Polyclonal Antibody

This gene encodes a member of the DEAD box protein family. DEAD box proteins| characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD)| are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure| such as translation initiation| nuclear and mitochondrial splicing| and ribosome and spliceosome assembly. Based on their distribution patterns| some members of this family are believed to be involved in embryogenesis| spermatogenesis| and cellular growth and division. The protein encoded by this gene is a nuclear matrix protein. Its amino acid sequence is highly similar to the amino acid sequences of the translation initiation factors eIF4AI and eIF4AII| two other members of the DEAD box protein family.