Phospho-14-3-3 Zeta (S58) Polyclonal Antibody
Product Specifications
Background
Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and sheep orthologs. Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity. Several transcript variants that differ in the 5' UTR but that encode the same protein have been identified for YWHAZ.
CAS Number
9007-83-4
Synonyms
YWHAZ; 14-3-3 protein zeta/delta; Protein kinase C inhibitor protein 1; KCIP-1
Host
Rabbit
Reactivity
Human;mouse;rat
Immunogen
The antiserum was produced against synthesized peptide derived from human 14-3-3 zeta around the phosphorylation site of Ser58. AA range:24-73
Clonality
Polyclonal
Applications
WB, IHC-p, IF, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
27745
Antibody Type
Primary antibody
Isotype
IgG
Available Sizes
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