Phospho-Bmx (Y566) Polyclonal Antibody
Product Specifications
Background
BMX (BMX non-receptor tyrosine kinase) encodes a non-receptor tyrosine kinase belonging to the Tec kinase family. The protein contains a PH-like domain, which mediates membrane targeting by binding to phosphatidylinositol 3,4,5-triphosphate (PIP3), and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway, and regulates differentiation and tumorigenicity of several types of cancer cells. Alternatively spliced transcript variants have been found for BMX.
CAS Number
9007-83-4
Synonyms
BMX; Cytoplasmic tyrosine-protein kinase BMX; Bone marrow tyrosine kinase gene in chromosome X protein; Epithelial and endothelial tyrosine kinase; ETK; NTK38
Host
Rabbit
Reactivity
Human;mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human ETK around the phosphorylation site of Tyr566. AA range:532-581
Clonality
Polyclonal
Applications
WB, IHC-p, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
78011
Antibody Type
Primary antibody
Isotype
IgG
Available Sizes
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