Phospho-Btk (Y551) Polyclonal Antibody
Product Specifications
Background
Bruton tyrosine kinase encoded by BTK plays a crucial role in B-cell development. Mutations in BTK cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms.
CAS Number
9007-83-4
Synonyms
BTK; AGMX1; ATK; BPK; Tyrosine-protein kinase BTK; Agammaglobulinaemia tyrosine kinase; ATK; B-cell progenitor kinase; BPK; Bruton tyrosine kinase
Host
Rabbit
Reactivity
Human;mouse;rat
Immunogen
The antiserum was produced against synthesized peptide derived from human BTK around the phosphorylation site of Tyr551. AA range:516-565
Clonality
Polyclonal
Applications
WB, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
76150
Antibody Type
Primary antibody
Isotype
IgG
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