TGR5 Polyclonal Antibody
Product Specifications
Background
GPBAR1 encodes a member of the G protein-coupled receptor (GPCR) superfamily. This enzyme functions as a cell surface receptor for bile acids. Treatment of cells expressing this GPCR with bile acids induces the production of intracellular cAMP, activation of a MAP kinase signaling pathway, and internalization of the receptor. The receptor is implicated in the suppression of macrophage functions and regulation of energy homeostasis by bile acids. Alternative splicing results in multiple transcript variants encoding the same protein.
CAS Number
9007-83-4
Synonyms
GPBAR1; TGR5; G-protein coupled bile acid receptor 1; G-protein coupled receptor GPCR19; hGPCR19; Membrane-type receptor for bile acids; M-BAR; hBG37; BG37
Host
Rabbit
Reactivity
Human
Immunogen
The antiserum was produced against synthesized peptide derived from human GPBAR. AA range:11-60
Clonality
Polyclonal
Applications
IF, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
35248
Antibody Type
Primary antibody
Isotype
IgG
Available Sizes
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