SP-100 Polyclonal Antibody
Product Specifications
Background
SP100 (SP100 nuclear antigen) encodes a subnuclear organelle and major component of the PML (promyelocytic leukemia)-SP100 nuclear bodies. PML and SP100 are covalently modified by the SUMO-1 modifier, which is considered crucial to nuclear body interactions. The encoded protein binds heterochromatin proteins and is thought to play a role in tumorigenesis, immunity, and gene regulation. Alternatively spliced variants have been identified for SP100; one of which encodes a high-mobility group protein.
CAS Number
9007-83-4
Synonyms
SP100; Nuclear autoantigen Sp-100; Lysp100b; Nuclear dot-associated Sp100 protein; Speckled 100 kDa
Host
Rabbit
Reactivity
Human
Immunogen
Synthesized peptide derived from SP-100 . at AA range: 250-330
Clonality
Polyclonal
Applications
WB, IHC-p, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
100417
Antibody Type
Primary antibody
Isotype
IgG
Available Sizes
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