SMRTe Polyclonal Antibody
Product Specifications
Background
NCOR2 (nuclear receptor corepressor 2) encodes a nuclear receptor co-repressor that mediates transcriptional silencing of certain target genes. The encoded protein is a member of a family of thyroid hormone- and retinoic acid receptor-associated co-repressors. This protein acts as part of a multisubunit complex which includes histone deacetylases to modify chromatin structure that prevents basal transcriptional activity of target genes. Aberrant expression of NCOR2 is associated with certain cancers. Alternate splicing results in multiple transcript variants encoding different isoforms.
CAS Number
9007-83-4
Synonyms
NCOR2; CTG26; Nuclear receptor corepressor 2; N-CoR2; CTG repeat protein 26; SMAP270; Silencing mediator of retinoic acid and thyroid hormone receptor; SMRT; T3 receptor-associating factor; TRAC; Thyr
Host
Rabbit
Reactivity
Human
Immunogen
The antiserum was produced against synthesized peptide derived from human NCOR2. AA range:511-560
Clonality
Polyclonal
Applications
IHC-p, IF, WB, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
274034
Antibody Type
Primary antibody
Isotype
IgG
Available Sizes
Frequently Asked Questions
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