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RUNX3 Polyclonal Antibody

Product Specifications

Background

RUNX3 encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this Runt-related transcription factor 3 and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Alternative splicing results in multiple transcript variants.

CAS Number

9007-83-4

Synonyms

RUNX3; AML2; CBFA3; PEBP2A3; Runt-related transcription factor 3; Acute myeloid leukemia 2 protein; Core-binding factor subunit alpha-3; CBF-alpha-3; Oncogene AML-2; Polyomavirus enhancer-binding prot

Host

Rabbit

Reactivity

Human;Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from human RUNX3. AA range:133-182

Clonality

Polyclonal

Applications

WB, ELISA

Stability

-20°C for one year

Concentration

1 mg/ml

Molecular Weight

44356

Antibody Type

Primary antibody

Isotype

IgG

Available Sizes

Frequently Asked Questions

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