RUNX3 Polyclonal Antibody
Product Specifications
Background
RUNX3 (runt related transcription factor 3) encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and RUNX3 is frequently deleted or transcriptionally silenced in cancer. Alternative splicing results in multiple transcript variants.
CAS Number
9007-83-4
Synonyms
RUNX3; AML2; CBFA3; PEBP2A3; Runt-related transcription factor 3; Acute myeloid leukemia 2 protein; Core-binding factor subunit alpha-3; CBF-alpha-3; Oncogene AML-2; Polyomavirus enhancer-binding prot
Host
Rabbit
Reactivity
Human
Immunogen
Synthesized peptide derived from the Internal region of human RUNX3.
Clonality
Polyclonal
Applications
WB, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
44356
Antibody Type
Primary antibody
Isotype
IgG
Available Sizes
Frequently Asked Questions
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