RCC2 Polyclonal Antibody
Product Specifications
Background
RCC2/TD-60 is a member of the RCC1 (regulator of chromosome condensation 1) family of guanine nucleotide exchange factors. RCC2/TD-60 is associated with the chromosome passenger complex (CPC), which also consists of aurora B kinase, borealin, INCENP (inner centromere protein) and survivin. The CPC acts at various stages of mitosis, interacts with microtubules and is required for proper chromosome segregation and cytokinesis. Regulation of aurora B kinase is key in the regulation of the CPC. In late mitosis, RCC2/TD-60 is required for spindle assembly and recruitment of survivin and aurora B. RCC2/TD-60 is also required for aurora B activation in vitro and localization of the CPC to centromeres.
CAS Number
9007-83-4
Synonyms
RCC2; KIAA1470; TD60; Protein RCC2; RCC1-like protein TD-60; Telophase disk protein of 60 kDa
Host
Rabbit
Reactivity
Human;Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human RCC2. AA range:473-522
Clonality
Polyclonal
Applications
WB, IHC-p, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
56085
Antibody Type
Primary antibody
Isotype
IgG
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
316900 100 µL
GATA binding Protein 1 (globin transcription factor 1)
Sign In for Pricing
View Details 
GTR15202696 1 Vial
Lentiviral mouse Cpb1 shRNA (UAS) - Lentiviral mouse Cpb1 shRNA (UAS, iRFP) plasmid
Sign In for Pricing
View Details 
S0741-01D-ML650 100 µL
SENP2, CT (Sentrin-specific Protease 2, Sentrin/SUMO-specific Protease SENP2, SMT3-Specific Isopeptidase 2, Smt3ip2, Axam2, KIAA1331) (MaxLight 650) discontinued
Sign In for Pricing
View Details