Rad51C Polyclonal Antibody
Product Specifications
Background
RAD51C is a member of the RAD51 family. RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51 and are known to be involved in the homologous recombination and repair of DNA. RAD51 paralog C can interact with other RAD51 paralogs and is reported to be important for Holliday junction resolution. Mutations in RAD51C are associated with Fanconi anemia-like syndrome. RAD51C is one of four localized to a region of chromosome 17q23 where amplification occurs frequently in breast tumors. Overexpression of the four genes during amplification has been observed and suggests a possible role in tumor progression. Alternative splicing results in multiple transcript variants.
CAS Number
9007-83-4
Synonyms
RAD51C; RAD51L2; DNA repair protein RAD51 homolog 3; R51H3; RAD51 homolog C; RAD51-like protein 2
Host
Rabbit
Reactivity
Human;Monkey
Immunogen
The antiserum was produced against synthesized peptide derived from human RAD51C. AA range:161-210
Clonality
Polyclonal
Applications
WB, IHC-p, IF, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
42190
Antibody Type
Primary antibody
Isotype
IgG
Available Sizes
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