Otubain-1 Polyclonal Antibody
Product Specifications
Background
The product of OTUB1 (OTU deubiquitinase, ubiquitin aldehyde binding 1) is a member of the OTU (ovarian tumor) superfamily of predicted cysteine proteases. The encoded protein is a highly specific ubiquitin iso-peptidase, and cleaves ubiquitin from branched poly-ubiquitin chains but not from ubiquitinated substrates. It interacts with another ubiquitin protease and an E3 ubiquitin ligase that inhibits cytokine gene transcription in the immune system. It is proposed to function in specific ubiquitin-dependent pathways, possibly by providing an editing function for polyubiquitin chain growth. Alternative splicing results in multiple transcript variants.
CAS Number
9007-83-4
Synonyms
OTUB1; OTB1; OTU1; HSPC263; Ubiquitin thioesterase OTUB1; Deubiquitinating enzyme OTUB1; OTU domain-containing ubiquitin aldehyde-binding protein 1; Otubain-1; hOTU1; Ubiquitin-specific-processing pro
Host
Rabbit
Reactivity
Human;Mouse;Rat
Immunogen
Synthesized peptide derived from Otubain-1 . at AA range: 20-100
Clonality
Polyclonal
Applications
WB, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
31284
Antibody Type
Primary antibody
Isotype
IgG
Available Sizes
Frequently Asked Questions
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