NF-E4 (Acetyl Lys43) Polyclonal Antibody
Product Specifications
Background
The erythroid-specific protein encoded by NFE4, and the ubiquitous transcription factor CP2, form the stage selector protein(SSP) complex, which is involved in preferential expression of the gamma-globin genes in fetal erythroid cells. Alternate use of an in-frame upstream non-AUG(CUG) translation initiation codon, and a downstream AUG codon, results in two isoforms. While the long isoform(22 kDa) acts as an activator, the short isoform(14 kDa) has been shown to repress gamma-globin gene expression. NFE4 is located in an intron of the FBXL13 gene on the opposite strand.
CAS Number
9007-83-4
Synonyms
NFE4; Transcription factor NF-E4
Host
Rabbit
Reactivity
Human
Immunogen
Synthesized acetyl-peptide derived from the human NF-E4 around the acetylation site of K43.
Clonality
Polyclonal
Applications
WB, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
19019
Antibody Type
Primary antibody
Isotype
IgG
Available Sizes
Frequently Asked Questions
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