Indole-2-carboxylic acid-13C
Indole-2-carboxylic acid-13C is the 13C-labeled Indole-2-carboxylic acid. Indole-2-carboxylic acid is a strong inhibitor of lipid peroxidation. Indole-2-carboxylic acid (I2CA) specifically and competitively inhibits the potentiation by glycine of NMDA-gated current[1][2].
Product Specifications
CAS Number
1216839-31-4
UNSPSC
12352005
Target
Endogenous Metabolite; iGluR; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Neuronal Signaling; Others
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/indole-2-carboxylic-acid-13c.html
Solubility
10 mM in DMSO
Smiles
O=[13C](O)C1=CC2=CC=CC=C2N1
Molecular Formula
C8 13CH7NO2
Molecular Weight
162.15
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]2-Indolecarboxylic acid.|[3]J E Huettner, et al. Indole-2-carboxylic Acid: A Competitive Antagonist of Potentiation by Glycine at the NMDA Receptor. Science. 1989 Mar 24;243 (4898) :1611-3.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Isoform
NMDA Receptor
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC700391-500 1x 500 µL
CD81 / TAPA-1 (1.3.3.22), CF770 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC680784-500 1x 500 µL
CD56 / NCAM (NCAM1/784), CF568 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC880282-500 1x 500 µL
HER-2 / CD340 (HRB2/282), CF488A conjugate, 0.1mg/mL
Sign In for Pricing
View Details