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N-CoR Polyclonal Antibody

Product Specifications

Background

NCOR1 (nuclear receptor corepressor 1) encodes a protein that mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. NCOR1 is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17. Alternate splicing results in multiple transcript variants. Pseudogenes of NCOR1 are found on chromosomes 17 and 20.

CAS Number

9007-83-4

Synonyms

NCOR1; KIAA1047; Nuclear receptor corepressor 1; N-CoR; N-CoR1

Host

Rabbit

Reactivity

Human;Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from human NCoR1. AA range:51-100

Clonality

Polyclonal

Applications

WB, IHC-p, IF, ELISA

Stability

-20°C for one year

Concentration

1 mg/ml

Molecular Weight

270210

Antibody Type

Primary antibody

Isotype

IgG

Available Sizes

Frequently Asked Questions

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