MRP-S24 Polyclonal Antibody

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. MRPS24 (mitochondrial ribosomal protein S24) encodes a 28S subunit protein. A pseudogene corresponding to MRPS24 is found on chromosome 11. Read-through transcription exists between MRPS24 and the upstream upregulator of cell proliferation (URGCP) gene.