Mi2-Beta Polyclonal Antibody
Product Specifications
Background
The product of CHD4 belongs to the SNF2/RAD54 helicase family. It represents the main component of the nucleosome remodeling and deacetylase complex and plays an important role in epigenetic transcriptional repression. Patients with dermatomyositis develop antibodies against this protein. Somatic mutations in this gene are associated with serous endometrial tumors. Alternative splicing results in multiple transcript variants encoding different isoforms.
CAS Number
9007-83-4
Synonyms
CHD4; Chromodomain-helicase-DNA-binding protein 4; CHD-4; ATP-dependent helicase CHD4; Mi-2 autoantigen 218 kDa protein; Mi2-beta
Host
Rabbit
Reactivity
Human;Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human CHD4. AA range:571-620
Clonality
Polyclonal
Applications
IHC-p, IF, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
217991
Antibody Type
Primary antibody
Isotype
IgG
Available Sizes
Frequently Asked Questions
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