MerTK Polyclonal Antibody

MERTK is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein, tyrosine-protein kinase mer, with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. Mutations in MERTK have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP).