MARCKS Polyclonal Antibody
Product Specifications
Background
Myristoylated alanine-rich C-kinase substrate encoded by MARCKS is a substrate for protein kinase C. It is localized to the plasma membrane and is an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane, leading to its presence in the cytoplasm. The protein is thought to be involved in cell motility, phagocytosis, membrane trafficking and mitogenesis.
CAS Number
9007-83-4
Synonyms
MARCKS; MACS; PRKCSL; Myristoylated alanine-rich C-kinase substrate; MARCKS; Protein kinase C substrate; 80 kDa protein, light chain; 80K-L protein; PKCSL
Host
Rabbit
Reactivity
Human;Mouse;Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human MARCKS. AA range:136-185
Clonality
Polyclonal
Applications
WB, IHC-p, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
31555
Antibody Type
Primary antibody
Isotype
IgG
Available Sizes
Frequently Asked Questions
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