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hnRNP H Polyclonal Antibody

Product Specifications

Background

HNRNPH2 belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. Heterogeneous nuclear ribonucleoprotein H2 encoded by HNRNPH2 has three repeats of quasi-RRM domains that binds to RNAs. It is very similar to the family member HNRPH1. This gene is thought to be involved in Fabray disease and X-linked agammaglobulinemia phenotype. Alternative splicing results in multiple transcript variants encoding the same protein. Read-through transcription between this locus and the ribosomal protein L36a gene has been observed.

CAS Number

9007-83-4

Synonyms

HNRNPH1; HNRPH; HNRPH1; Heterogeneous nuclear ribonucleoprotein H; hnRNP H; HNRNPH2; FTP3; HNRPH2; Heterogeneous nuclear ribonucleoprotein H2; hnRNP H2; FTP-3; Heterogeneous nuclear ribonucleoprotein

Host

Rabbit

Reactivity

Human;Mouse;Rat

Immunogen

The antiserum was produced against synthesized peptide derived from human hnRNP H. AA range:156-205

Clonality

Polyclonal

Applications

WB, IHC-p, ELISA

Stability

-20°C for one year

Concentration

1 mg/ml

Molecular Weight

49264

Antibody Type

Primary antibody

Isotype

IgG

Available Sizes

Frequently Asked Questions

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