HMG-1 (Acetyl Lys12) Polyclonal Antibody
Product Specifications
Background
HMGB1 encodes a protein that belongs to the High Mobility Group-box superfamily. The encoded non-histone, nuclear DNA-binding protein regulates transcription, and is involved in organization of DNA. High mobility group box 1 plays a role in several cellular processes, including inflammation, cell differentiation and tumor cell migration. Multiple pseudogenes of HMGB1 have been identified. Alternative splicing results in multiple transcript variants that encode the same protein.
CAS Number
9007-83-4
Synonyms
HMGB1; HMG1; High mobility group protein B1; High mobility group protein 1; HMG-1
Host
Rabbit
Reactivity
Human;Mouse;Rat
Immunogen
Synthesized acetyl-peptide derived from the N-terminal region of human HMG-1 around the acetylation site of K12.
Clonality
Polyclonal
Applications
WB, IHC-p, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
24894
Antibody Type
Primary antibody
Isotype
IgG
Available Sizes
Frequently Asked Questions
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