G Alpha olf Polyclonal Antibody

GNAL encodes a stimulatory G protein alpha subunit which mediates odorant signaling in the olfactory epithelium. Guanine nucleotide-binding protein G(olf) subunit alpha couples dopamine type 1 receptors and adenosine A2A receptors and is widely expressed in the central nervous system. Mutations in GNAL have been associated with dystonia 25 and this gene is located in a susceptibility region for bipolar disorder and schizophrenia. Alternative splicing results in multiple transcript variants.