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GRK 2 Polyclonal Antibody

Product Specifications

Background

Beta-adrenergic receptor kinase 1 phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. Beta-adrenergic receptor kinase 1 is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart.

CAS Number

9007-83-4

Synonyms

ADRBK1; BARK; BARK1; GRK2; Beta-adrenergic receptor kinase 1; Beta-ARK-1; G-protein coupled receptor kinase 2

Host

Rabbit

Reactivity

Human;Mouse;Rat

Immunogen

The antiserum was produced against synthesized peptide derived from human GRK2. AA range:640-689

Clonality

Polyclonal

Applications

WB, IHC-p, ELISA

Stability

-20°C for one year

Concentration

1 mg/ml

Molecular Weight

79574

Antibody Type

Primary antibody

Isotype

IgG

Available Sizes

Frequently Asked Questions

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