Filamin 1 Polyclonal Antibody
Product Specifications
Background
Filamin-A encoded by FLNA is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. Filamin-A is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. Filamin-A interacts with integrins, transmembrane receptor complexes, and second messengers. Defects in FLNA are a cause of several syndromes, including periventricular nodular heterotopias (PVNH1, PVNH4), otopalatodigital syndromes (OPD1, OPD2), frontometaphyseal dysplasia (FMD), Melnick-Needles syndrome (MNS), and X-linked congenital idiopathic intestinal pseudoobstruction (CIIPX). Two transcript variants encoding different isoforms have been found for this gene.
CAS Number
9007-83-4
Synonyms
FLNA; FLN; FLN1; Filamin-A; FLN-A; Actin-binding protein 280; ABP-280; Alpha-filamin; Endothelial actin-binding protein; Filamin-1; Non-muscle filamin
Host
Rabbit
Reactivity
Human;Mouse;Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human Filamin A. AA range:2121-2170
Clonality
Polyclonal
Applications
WB, IHC-p, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
280608
Antibody Type
Primary antibody
Isotype
IgG
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
TRC-D141760-25MG 25 mg
(2R,3R)-(2R,3R)-3,4-Dihydro-3,7-dihydroxy-2-(4-hydroxyphenyl)-2H-1-benzopyran-5-yl beta-D-glucopyranoside
Sign In for Pricing
View Details 
#29083R-5ug 1x 5 µg
Annexin V, CF®450 Conjugate, Azide-Free, Lyophilized
Sign In for Pricing
View Details 
