ET-1 Polyclonal Antibody
Product Specifications
Background
EDN1 encodes a preproprotein that is proteolytically processed to generate a secreted peptide that belongs to the endothelin/sarafotoxin family. This peptide is a potent vasoconstrictor and its cognate receptors are therapeutic targets in the treatment of pulmonary arterial hypertension. Aberrant expression of this gene may promote tumorigenesis. Alternative splicing results in multiple transcript variants.
CAS Number
9007-83-4
Synonyms
EDN1; Endothelin-1; Preproendothelin-1; PPET1
Host
Rabbit
Reactivity
Human
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human EDN1. AA range:131-180
Clonality
Polyclonal
Applications
WB, IHC-p, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
24425
Antibody Type
Primary antibody
Isotype
IgG
Available Sizes
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