Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Ephrin-B3 Polyclonal Antibody

Product Specifications

Background

EFNB3, a member of the ephrin gene family, is important in brain development as well as in its maintenance. Moreover, since levels of EFNB3 expression were particularly high in several forebrain subregions compared to other brain subregions, it may play a pivotal role in forebrain function. The EPH and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, particularly in the nervous system. EPH Receptors typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin ligands and receptors have been named by the Eph Nomenclature Committee (1997). Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are similarly divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands.

CAS Number

9007-83-4

Synonyms

EFNB3; EPLG8; LERK8; Ephrin-B3; EPH-related receptor transmembrane ligand ELK-L3; EPH-related receptor tyrosine kinase ligand 8; LERK-8

Host

Rabbit

Reactivity

Human;Mouse;Rat

Immunogen

The antiserum was produced against synthesized peptide derived from human EFNB3. AA range:221-270

Clonality

Polyclonal

Applications

WB, IHC-p, ELISA

Stability

-20°C for one year

Concentration

1 mg/ml

Molecular Weight

35835

Antibody Type

Primary antibody

Isotype

IgG

Available Sizes

Frequently Asked Questions