Cortactin Polyclonal Antibody
Product Specifications
Background
Cortactin, encoded by CTTN gene (formerly EMS1), was originally identified as a substrate of the Src kinase. It is a cytoskeletal protein that interacts with F-actin and Arp2/3 complex and plays an important role in regulation of actin assembly and cytoskeleton dynamics. Overexpression of cortactin increases cell migration, and is thought to contribute to the invasive phennotype of breast cancer and several other tumors. Three isoforms of cortactin exist due to the alternative splicing.
CAS Number
9007-83-4
Synonyms
CTTN; EMS1; Src substrate cortactin; Amplaxin; Oncogene EMS1
Host
Rabbit
Reactivity
Human;Mouse;Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human Cortactin. AA range:388-437
Clonality
Polyclonal
Applications
WB, IHC-p, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
61636
Antibody Type
Primary antibody
Isotype
IgG
Available Sizes
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