Cofilin Polyclonal Antibody
Product Specifications
Background
Cofilin 1 encoded by CFL1 can polymerize and depolymerize F-actin and G-actin in a pH-dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.
CAS Number
9007-83-4
Synonyms
CFL1; CFL; Cofilin-1; 18 kDa phosphoprotein; p18; Cofilin; non-muscle isoform; CFL2; Cofilin-2; Cofilin, muscle isoform
Host
Rabbit
Reactivity
Human;Mouse;Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human Cofilin. AA range:61-110
Clonality
Polyclonal
Applications
WB, IF, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
18371
Antibody Type
Primary antibody
Isotype
IgG
Available Sizes
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