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Choactase Polyclonal Antibody

Product Specifications

Background

CHAT encodes an enzyme which catalyzes the biosynthesis of the neurotransmitter acetylcholine. CHAT product (choline O-acetyltransferase) is a characteristic feature of cholinergic neurons, and changes in these neurons may explain some of the symptoms of Alzheimer's disease. Polymorphisms in CHAT have been associated with Alzheimer's disease and mild cognitive impairment. Mutations in CHAT are associated with congenital myasthenic syndrome associated with episodic apnea. Multiple transcript variants encoding different isoforms have been found for CHAT, and some of these variants have been shown to encode more than one isoform.

CAS Number

9007-83-4

Synonyms

CHAT; Choline O-acetyltransferase; CHOACTase; ChAT; Choline acetylase

Host

Rabbit

Reactivity

Human;Mouse;Rat

Immunogen

The antiserum was produced against synthesized peptide derived from human Choactase. AA range:334-383

Clonality

Polyclonal

Applications

WB, ELISA

Stability

-20°C for one year

Concentration

1 mg/ml

Molecular Weight

82568/74361/70394

Antibody Type

Primary antibody

Isotype

IgG

Available Sizes

Frequently Asked Questions

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