Cdc23 Polyclonal Antibody
Product Specifications
Background
Cell division cycle 23 encoded by CDC23 shares strong similarity with Saccharomyces cerevisiae Cdc23, a protein essential for cell cycle progression through the G2/M transition. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eukaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction.
CAS Number
9007-83-4
Synonyms
CDC23; ANAPC8; Cell division cycle protein 23 homolog; Anaphase-promoting complex subunit 8; APC8; Cyclosome subunit 8
Host
Rabbit
Reactivity
Human;Mouse;Monkey
Immunogen
The antiserum was produced against synthesized peptide derived from human APC8. AA range:251-300
Clonality
Polyclonal
Applications
WB, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
68286
Antibody Type
Primary antibody
Isotype
IgG
Available Sizes
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