BMP-5 Polyclonal Antibody
Product Specifications
Background
BMP5 encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone and cartilage development. Polymorphisms in this gene may be associated with osteoarthritis in human patients. This gene is differentially regulated in multiple human cancers. BMP5 encodes distinct protein isoforms that may be similarly proteolytically processed.
CAS Number
9007-83-4
Synonyms
BMP5; Bone morphogenetic protein 5; BMP-5
Host
Rabbit
Reactivity
Human;Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human BMP-5. AA range:114-163
Clonality
Polyclonal
Applications
WB, IHC-p, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
51737
Antibody Type
Primary antibody
Isotype
IgG
Available Sizes
Frequently Asked Questions
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