ASCL1 Polyclonal Antibody
Product Specifications
Background
TRIP4 (thyroid hormone receptor interactor 4) encodes a subunit of the tetrameric nuclear activating signal cointegrator 1 (ASC-1) complex, which associates with transcriptional coactivators, nuclear receptors and basal transcription factors to facilitate nuclear receptors-mediated transcription. This protein is localized in the nucleus and contains an E1A-type zinc finger domain, which mediates interaction with transcriptional coactivators and ligand-bound nuclear receptors, such as thyroid hormone receptor and retinoid X receptor alpha, but not glucocorticoid receptor. Mutations in TRIP4 are associated with spinal muscular atrophy with congenital bone fractures-1 (SMABF1).
CAS Number
9007-83-4
Synonyms
Achaete-scute homolog 1 (ASH-1) (hASH1) (Class A basic helix-loop-helix protein 46) (bHLHa46)
Host
Rabbit
Reactivity
Human;Mouse;Rat
Immunogen
Synthetic peptide from human protein at AA range: 190-236
Clonality
Polyclonal
Applications
IHC-p, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
66146
Antibody Type
Primary antibody
Isotype
IgG
Available Sizes
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